Worker path maps are new in 6.4-2.
Documentation for worker path maps can be found here:
http://docs.pipelinefx.com/display/QUB064/worker_path_mapNote: For most types or submission, you *must* set the convert_path job flag for worker-side path translation to take place.
Worker path maps are designed to translate the paths of project files, but there is no reason they can't be used to convert the paths of the applications themselves. Simply use the Windows path on the left and the OS X path on the right (or vice versa, or substitute Linux for either OS).
On that topic, there is a new jobtype called "AppFinder" that is designed specifically for finding paths to applications on heterogeneous farms.
Documentation for AppFinder jobs can be found here:
http://docs.pipelinefx.com/display/QUB064/AppFinder+JobsAppFinder should be a fire & forget type of solution for most situations, but can work in conjunction with worker_path_map when the path to the executable is not in a standard location.
Note: Python *must* be installed on the executing worker & be in $PATH for the executing user.
Worker_path_maps can be set either in the worker's local qb.conf or in the central qbwrk.conf -- you are able to set them on a per-host basis.