Ah, yes, I forgot to post back, but I had that at 256 and changed back to 128 and seems to have resolved it. Still curious why I'd cause issues all of a sudden, I changed that about two weeks into deployment...
Also, was 256 a bad choice? Initially I had changed it thinking it had something to do with amount of users using the Qube! client software, some of them were getting time-outs randomly...
Thanks for the reply,
Josh